Doctoral Studies

Biophysics - Field

Brief description of field

The field of study is oriented on two basic topics of this interdisciplinary field, namely physical inherent laws significant for fundamental biological processes and action of physical factors on living organisms and their components. A particular attention is paid to the studies of conformation and physico-chemical properties of biopolymers, their mutual interactions, interactions with other low-molecular-mass compounds of biological significance (in particular antitumor drugs) and to properties of biomacromolecules at interfaces. The field is also oriented on the studies of action of physical environmental factors (ultrasound, hydrodynamic forces, electric, magnetic, and electromagnetic field, high frequency plasma, UV and ionizing radiation) on biological objects. The studies are mostly performed using spectroscopic methods (circular and linear dichroism, fluorescence, NMR a Raman spectrometry), calorimetry, electrochemical methods (impedance spectroscopy, voltammetry, pulse polarography), electrophoresis, methods of radiation biophysics and computational chemistry (computational modeling of structures of molecules of biological significance), cytometry with high resolution.

The field of biophysics has more than forty years’ lasting tradition at the Faculty of Sciences in both graduate and doctoral studies. A very close collaboration between the Faculty of Sciences and the Institute of Biophysics, Academy of Sciences of the Czech Republic always played a key role in these studies.

Profile of a typical graduate

The graduate has a relatively universal education in the fields, such as physics, physico-chemical properties of molecules of biological significance, their complexes and interactions with physical and chemical environmental factors. He/she can relatively easily become adapted to other spheres of science, such as physical aspects of molecular mechanisms underlying fundamental biological processes involving for instance transfer of genetic information, cell cycle, photosynthesis. Due to the character of the study he/she is also capable of understanding the fundamental problems of closely related fields (physics, mathematics, biochemistry, microbiology, molecular biology) so that he/she is well accepted and could apply this knowledge in both fundamental and applied research oriented on problems of ecology, agriculture, health service, and food production.

Requirements for applicants

  1. The applicant selects before the entrance interview a topic of his/her dissertation thesis and corresponding supervisor from the list approved by the field commission.
  2. The applicant appears in the entrance interview along with his/her supervisor or his/her representative. The applicant must demonstrate during this interview fundamental knowledge in physics, physico-chemistry, biophysics, biochemistry, and molecular biology. Ability of active communication in English is a pre-requisite.

Study requirements and completion of studies

Individual study plan

The supervisor is mainly responsible for course and guidance of the student in the doctoral study. The supervisor determines (in agreement with general rules of the doctoral study program) the extent of theoretical training and is particular about high scientific quality of the dissertation thesis. He/she submits at least once a year a report on the training and work of the PhD student. The field council requires an obligatory participation of the PhD students in seminars organized by the field council.

Content and extent of the state doctor examination, required knowledge

The PhD student must pass, before defense of his/her dissertation thesis, state doctor examination. The PhD student will receive in advance the list of questions. The regular PhD students must pass this examination before they finish the third year of their study. The external PhD students (in combined version of the doctoral study) must pass this examination before the end of the fifth year of their study.

Requirements of the doctorate dissertation thesis

The dissertation thesis must be based on absolutely original results, which were published (or accepted for publication) in renowned, international and refereed journals. The dissertant must be the first author of at least one paper published in the journal having impact factor of 1.0 or higher.

List of modern topics of dissertation theses for the given academic year is given below at the page.

Individual study plan

The supervisor is mainly responsible for course and guidance of the student in the doctoral study. The supervisor determines (in agreement with general rules of the doctoral study program) the extent of theoretical training and is particular about high scientific quality of the dissertation thesis. He/she submits at least once a year a report on the training and work of the PhD student. The field council requires an obligatory participation of the PhD students in seminars organized by the field council.

List of members of doctoral committee

List of supervisors

Commission for state doctoral exams and defenses

List of current doctoral topics

Department pages


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