National Centre for Biomolecular Research

Research and Educational Activities

The National Centre for Biomolecular Research (NCBR) is an independent institute of the Faculty of Science, Masaryk University, Brno. The main activities of the Centre involve research in specific areas of chemistry and molecular biology as well as teaching at the undergraduate and Ph.D. levels. Staff members, Ph.D. students, postdoctoral fellows, and diploma students contribute to the research output of the Centre.

The institute is well furnished with modern laboratory equipment and research infrastructure. It includes instrumentation for structure characterization (NMR spectroscopy, protein crystallization), thermodynamic and kinetic measurements, and nanobiotechnology. Instrumentation for experimental studies is complemented with strong computational background for theoretical studies. The focus of scientific work is placed primarily on biologically interesting molecules, especially proteins, nucleic acids, carbohydrates and on their interactions. The main activities of the Centre involve research in computational and theoretical methods, molecular modeling, NMR spectroscopy, glycobiochemistry and protein engineering of lectins. Individual NCBR research projects focus on molecular recognition and host/pathogen interactions, RNA quality control, DNA repair mechanisms, cholinesterases in relation to neural diseases and chemical weapons, and other timely subjects.

Undergraduate and/or Ph.D. study at the Centre is particularly suitable for the students of biomolecular chemistry, organic chemistry, theoretical and physical chemistry, biochemistry, environmental chemistry and biphysics.

Workgroups

  • Laboratory of Computational Chemistry
  • Laboratory of Nuclear Magnetic Resonance
  • Laboratory of Glycobiochemistry
  • Laboratory of Structure and Dynamics of Nucleic Acids
  • Laboratory of Recombination and DNA Repair
  • Nanobiotechnology Laboratory
  • Laboratory of RNA /Protein Interactions
  • Laboratory of RNA Processing and Degradation

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