Doctoral Theses

  • Anna Vyhlídalová Kotrbová: Functional and biochemical analysis of extracellular vesicles from ovarian cancer ascites (2022)
  • Petra Paclíková: Dishevelled functional analysis using CRISPR/Cas9 editing technique (2021)
  • Zankruti Dave: ErRORs in cellular crosstalk – importance in development and disease (2020)
  • Jakub Harnoš: The Consequences of CK1ε-induced Phosphorylation of the Selected Components of the WNT/β-catenin Pathway: Structural Biology Point of View (2018)
  • Karol Kaiser: Wnt secretion and transport in the mammalian nervous system (2018)
  • Pavlína Janovská: The Role of Migration in the Pathogenesis of Chronic Lymphocytic Leukemia (2018)
  • Kateřina Straková: Interaction of Class Frizzled receptors with G proteins and Dishevelled (2017)
  • Igor Červenka: Regulation of WNT signaling components by kinases: unconventional aspects (2014)
  • Markéta Kaucká: Planar cell polarity pathway in the pathogenesis of chronic lymphocytic leukemia (2013)
  • Sri Ranjani Ganji: Identification and Validation of Dvl interacting partners using Proteomics approach (2013)
  • Ondřej Bernatík: Posttranslational modifications of Dishevelled (2012)

Diploma Theses

  • Jana Kramářová: Role of Wnt signaling in ovarian cancer progression (2022)
  • Jan Krondráf: Expression and function of ROR1 receptor of the Wnt/PCP signaling pathway in B cells of healthy donors and CLL patients (2021)
  • Michaela Nosková: Targeting isoforms of casein kinase 1 in the human melanoma (2021)
  • Tomáš Gybel´: Utilizing CRISPR/Cas9 technology for the functional characterization of casein kinase 1 isoforms in the Wnt signaling pathway (2019)
  • Michaela Gregorová: Novel casein kinase 1 inhibitors for the treatment of leukemias and lymphomas (2019)
  • Kristína Gömöryová: The function of Pin1 isomerase in the Wnt signalling pathway (2017)
  • Miroslav Hutňan: Implementation of quantiative proteomics into the analysis of Wnt signaling (2017)
  • Anna Kotrbová: Role of ascites in ovarian cancer progression (2016)
  • Petra Paclíková: Functional analysis of cells lacking Dishevelled (2016)
  • Marek Kravec: A novel post-translational modification of Dishevelled (2016)
  • Matěj Rádsetoulal: Description of Dishevelled phosphorylation map (2016)
  • Lucie Smyčková: APP proteins in the pathogenesis of chronic lymphocytic leukemia (2016)
  • Pavlína Janovská: Novel mechanisms in the pathogenesis of chronic lymphocytic leukemia (2013)
  • Jakub Harnoš: Structure-function study of two regions of Dishevelled: DEP domain and the C-terminus (2013)
  • Jana Valnohová: The role of Dishevelled in the G2/M phase of the cell cycle (2013)
  • Martin Běhal: Analysis of the novel components of non-canonical Wnt pathway (2013)
  • Alena Salašová: Wnt signaling and cell cycle (2011)
  • Igor Červenka: Kinase analysis in the Wnt signalling (2010)
  • Jan Mašek: Interaction of Wnt and FGF signalling (2010)

Bachelor Theses

  • Petra Bačovská: Filopodia and their role in cell signalling (2022)
  • Martin Smolko: Role of extracellular vesicles in ovarian carcinoma (2022)
  • Milena Mařáková: In vitro experimental systems for analysis of tumor cell interactions with their microenvironment (2020)
  • Jan Krondráf: Diagnostics of b-lymphocyte-derived malignancies and normal b-lymhocyte development from the point of single cell-based methods (2019)
  • Jana Kramářová: PARP inhibitors – a novel treatment option for ovarian cancer (2019)
  • Michaela Nosková: Cell migration in the biology and diagnostics of melanoma (2019)
  • Nikodém Zezula: Role of CTHRC1 protein in normal and malignant cells (2018)
  • Štěpán Čada: Microscopic analysis of cellular polarization – methods to visualize polarized cells and protein complexes (2018)
  • Jana Lapinová: Biological function and diagnostic potential of exosomes in ovarian carcinoma (2018)
  • Miroslav Micka: Analysis of protein-protein interactions in the living cells (2018)
  • Petra Kompaníková: The role of Wnt5a in tissue and organ morphogenesis (2018)
  • Kristína Gömöryová: Analysis of protein conformation in the living cell (2016)
  • Tomáš Gybeľ: CRISPR technology for manipulation of mammalian cells (2016)
  • Anna Kotrbová: Wnt signaling in the ovarian cancer (2014)
  • Petra Paclíková: Cellular signaling controlled by semaphorins (2014)
  • Marek Kravec: Post-translational modifications of tubulin and their role in cellular biology (2014)
  • Lucie Smyčková: In vivo and in vitro models for study of chronic lymphocytic leukemia (2014)
  • Igor Greif: Wnt pathway in the pathogenesis of chronic lymphocytic leukemia (2014)
  • Miroslav Hutňan: Mass spectrometry in the analysis of cellular signaling in mammalian cells (2014)
  • Pavlína Janovská: Wnt/beta-catenin signaling and cancer stem cell (2011)
  • Jana Valnohová: Wnt signaling in leukemia (2011)
  • Martin Běhal: Small GTPases and their role for the biology of the cell (2011)
  • David Kubíček: Regulation of cell movements and cytoskeleton (2011)
  • Alena Salašová: Molecular-physiological basics of cell senescence and immortalization (2009)
  • Igor Červenka: Identification of candidate cytoplasmic regulators of Wnt signalling in silico (2008)
  • Jan Mašek: The role of Dishevelled kinases in Wnt signalling (2008)