That’s the one thing I like on polymer monoliths the most.
By proper selection of polymerization mixture composition or careful post-polymerization modification, one can prepare not only chromatographic stationary phases, but also enzymatic reactors, sample preparation units, derivatization cartriges, and mechanical valves.
In my research I focus on tailored preparation of monolithic stationary phases and their specific application in various separation problems.
Currently, we are working on preparation of polymer-based monolithic capillary columns allowing chromatographic screening of dopamine metabolism-related disorders, such as Parkinson’s disease.
We have also developed an monolithic capillary column with an integrated electrochemical detector for a specific determination of neurotransmitters in human urine.
I am a co-author of very first publications dealing with a hypercrosslinking modification of polymer monoliths and their application in fast and efficient separations of small molecules.
Pore formation in monolithic materials and their proper chromatographic characterization has been one of my research interests for years.