Projects

Running projects

  • 2022-2025 | Finding new therapeutic targets for the treatment of giant cell tumor of bone (Project No. NU22-10-00054 of the Ministry of Healthcare of the Czech Republic; duration: 2022-2025; principal investigator: J. Neradil)
  • 2020-2023 | Stemness factors and the p53 family proteins in pediatric sarcomas: A dysregulated transcriptional network as a potential therapeutic target (Project No. NU20J-07-00004 of the Ministry of Healthcare of the Czech Republic; duration: 2020-2023; principal investigator: J. Škoda)
  • 2018-2023 | ENOCH – Molecular, Cellular and Clinical Approach to Healthy Ageing (Project OP VVV CZ.02.1.01/0.0/0.0/16_019/0000868; duration: 2018-2023; principal investigator: G. B. Stokin)

Completed projects

  • Mitochondrial dynamics and autophagy: A missing link between dedifferentiation and development of resistance in pediatric solid tumors (Project No. 20-00987Y of the Czech Science Foundation; duration: 2020-2022; principal investigator: J. Škoda)
  • Therapeutic potential of novel thiosemicarbazones in pediatric oncology: the possibilities how to overcome Pgp-mediated drug resistance (Project No. 17-33104A of the Ministry of Healthcare of the Czech Republic; duration: 2017-2022; principal investigator: R. Veselska)
  • Online collection of case studies for innovating bioethics courses at MU (Project MUNI/FR/1253/2019 MU Development Fund; duration: 2020; principal investigator: P. Chlapek)
  • Translational Medicine (Project NPU II LQ1605; duration: 2016-2020; principal investigator: G. B. Stokin)
  • Receptor tyrosin kinases and downstream signaling pathways as possible therapeutic targets in pediatric refractory solid tumors (Project No. 16-34083A of the Ministry of Healthcare of the Czech Republic; duration: 2016-2019; principal investigator: J. Sterba)
  • Candidate biomarkers of resistance to retinoids in children with high-risk neuroblastoma (Project No. 15-34621A of the Ministry of Healthcare of the Czech Republic; duration: 2015-2018; principal investigator: R. Veselska)
  • Identification and characterization of cancer stem cells in pediatric sarcomas (Grant No. NT13443-4 of the Ministry of Healthcare of the Czech Republic; duration: 2012-2015; principal investigator: R. Veselska)
  • DHFR- and non-DHFR-mediated effects of methotrexate on cellular level: a study on cell lines derived from pediatric solid tumors (Grant No. NT14327-3 of the Ministry of Healthcare of the Czech Republic; duration: 2013-2015; principal investigator: J. Štěrba)
  • IntegRECAMO: Intellectual Anchor (Project OP VK CZ.1.07/2.3.00/20.0097; duration: 2012-2015; principal investigator: D. Valik)
  • Center of Experimental Biomedicine (CEB) (Project OP VK CZ.1.07/2.3.00/20.0183; duration: 2012-2015; principal investigator: J. Smarda)
  • Partnership and Networks for Cooperation in Experimental Biology (PASSEB) (Project OP VK CZ.1.07/2.4.00/31.0155; duration: 2013-2014; principal investigator: J. Smarda)
  • Cellular and molecular responses induced by combined application of differentiating and antiangiogenic agents in sarcoma cell lines (SARCOMBAT) (Grant No. 2SGA2834 of the South Moravian Region and 7th FP EC – SoMoPro / Incoming Grants: 2011-2013; principal investigator: M. Krzyzankova)
  • Modular Structure of the Studies Focused on Experimental Biology (MOSSEB) (Project OP VK CZ.1.07/2.2.00/07.0429; duration: 2009-2012; principal investigator: J. Šmarda)
  • The Role of p73 Protein Isoforms in the Pathogenesis of Medulloblastoma: Immunocytochemical and Microarray Study (Grant No. NS10218-3 of the Ministry of Healthcare of the Czech Republic; duration:2009-2011; principal investigator: K. Zitterbart)
  • Molecular Basis of Cell and Tissue Regulations (Long-term research plan No. MSM0021622415 of the Ministry of Education of the Czech Republic; duration: 2005-2011; principal investigator: J. Fajkus)
  • Molecular Mechanisms of the Cell Proliferation and Differentiation (Grant No. GD204/08/H054 of the Czech Science Foundation; duration: 2008-2011; principal investigator: J. Smarda)
  • Innovation of the Interdisciplinary Education in Bioethics at Masaryk University (Grant No. 1989 of the Ministry of Education of the Czech Republic; duration: 2010; principal investigator: J. Kure)
  • Modulation of Antineoplastic Effect of Retinoids by LOX/COX Inhibitors on the Model of Solid Childhood Tumors: In Vitro Study (Grant No. NR/9341-3 of the Ministry of Healthcare of the Czech Republic; duration: 2007-2009; principal investigator: R. Veselska)
  • Importance of Molecular Cytogenetic Markers for Diagnosis and Prediction of Embryonal Childhood Tumors (Grant No. NR/9125-4 of the Ministry of Healthcare of the Czech Republic; duration: 2006-2009; principal investigator: R. Veselska)
  • Innovation of the Course: Medical Ethics (Grant No. 1309 of the Ministry of Education of the Czech Republic; duration: 2008; principal investigator: J. Kure)
  • New Course: Animal Cell Biology (Grant No. 2699 of the Ministry of Education of the Czech Republic; duration: 2007; principal investigator: R. Veselska)
  • Gene Diagnostic and Therapy of Multiform Glioblastoma (Project COST OC B 19.001: 2001-2006; principal investigator: P. Cejpek)
  • Effects of the Non-Invasive Laser Treatment on the Cell Structure (Grant No. 304/04/1386 of the Czech Science Foundation: 2004-2006; principal investigator: R. Janisch)
  • Online Textbooks for Interdisciplinary Education in Bioethics (Grant No. 2475 of the Ministry of Education of the Czech Republic; duration: 2005; principal investigator: R. Veselska)
  • EURETHNET: European Information Network „Ethics in Medicine and Biotechnology“ (Project No. FP5 QLRT-2001-00057: 2003-2004; coordinator: University of Goettingen, Germany)
  • Innovation of the Medical Biology Practicals (Grant No. 450 of the Ministry of Education of the Czech Republic; duration: 2003; principal investigator: R. Veselska)
  • Influence of Caffeic Acid on the Induction of Differentiation of the HL-60 Cells (Grant No. 620 of the Ministry of Education of the Czech Republic; duration: 2002; principal investigator: R. Veselska)
  • Changes of the Cytoskeleton in Tumor Cell Lines during Induced Apoptosis in Relation to Different Stages of Differentiation (Grant No. 304/00/0403 of the Czech Science Foundation; duration: 2000-2002; principal investigator: A. Svoboda)
  • Influence of Micromanipulations on the Cytoskeleton of Human Cells In Vitro (Grant No. 304/98/P222 of the Czech Science Foundation; duration: 09/1998 – 08/2001; principal investigator: R. Veselska)
  • The Relation of the Cytoskeleton to the Apoptosis in Leukemia HL-60 Cell Line (Grant No. 1704 of the Ministry of Education of the Czech Republic; duration: 2000; principal investigator: R. Veselska)
  • Interaction of UV Radiation with Cytoskeleton of Human Epidermoid Cells In Vitro (Grant No. 402 of the Ministry of Education of the Czech Republic; duration: 1999; principal investigator: R. Veselska)
  • The Role of the Cytoskeleton in Reparation of Mechanical Damage of the Cell (Grant No. 204/96/0240 of the Czech Science Foundation; duration: 1996-1998; principal investigator: R. Janisch)
  • The Use of Cell Cultures in Biology Teaching at Medical School (Grant No. 227 of the Ministry of Education of the Czech Republic; duration: 1997; principal investigator: A. Svoboda)