Iron-Chelation Treatment by Novel Thiosemicarbazone Targets Major Signaling Pathways in Neuroblastoma. Int. J. Mol. Sci. 2022, 23(1): 376.
Peter Macsek, Jan Skoda,Maria Krchniakova, Jakub Neradil, Renata Veselska
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New review in Antioxidants
Tumour Microenvironment Stress Promotes the Development of Drug Resistance. Antioxidants 2021, 10(11): 1801.
Nicole A. Seebacher, Maria Krchniakova, Alexandra E. Stacy, Jan Skoda, Patric J. Jansson.
New paper in Cancer Letters (IF 8.679)!
Noncanonical roles of p53 in cancer stemness and their implications in sarcomas. Cancer Letters 2022, 525: 131-145.
Lucie Curylova, Helena Ramos, Lucília Saraiva, Jan Skoda.
New paper in Pediatric Blood & Cancer!
Bromodomain 4 inhibition leads to MYCN downregulation in Wilms tumor. Pediatr Blood Cancer 2021, e29401.
Andrew D. Woods, Noah E. Berlow, Michael V. Ortiz, Filemon Dela Cruz, Armaan Siddiquee, Diego F. Coutinho, Reshma Purohit, Katherine E. Tranbarger Freier, Joel E. Michalek, Melvin Lathara, Kevin Matlock, Ganapati Srivivasa, Brigitte Royer-Pokora, Renata Veselska, Andrew L. Kung, Charles Keller
New paper in Cell Reports (IF 9.423)!
A selective p53 activator and anticancer agent to improve colorectal cancer therapy. Cell Rep 2021, 35(2):1089.
Helena Ramos, Maria I L Soares, Joana Silva, Liliana Raimundo, Juliana Calheiros, Célia Gomes, Flávio Reis, Filipe A Monteiro, Cláudia Nunes, Salette Reis, Bartolomeo Bosco, Silvano Piazza, Lucília Domingues, Petr Chlapek, Petr Vlcek, Pavel Fabian, Ana Teresa Rajado, A T P Carvalho, Renata Veselska, Alberto Inga, Teresa M V D Pinho E Melo, Lucília Saraiva
New paper in Cancers
Paukovcekova et al.: Novel Thiosemicarbazones Sensitize Pediatric Solid Tumor Cell-Types to Conventional Chemotherapeutics through Multiple Molecular Mechanisms. Cancers 2020, 12:3781.
Karolina receives the Dean’s Award
Our student Karolina Borankova has been awarded for her excellent research results obtained during her diploma thesis and she has received the Dean’s Award for the best students in the Bachelor’s or Master’s programme. In her research, Karolina focused on investigating the role of mitochondria in cancer stem cells in pediatric tumors.