Paper in EMBO Journal: A novel mechanism of neuroblastoma multidrug resistance identified

Reduced ER–mitochondria connectivity promotes neuroblastoma multidrug resistance. The EMBO Journal (2022)41:e108272

Jorida Çoku, David M Booth, Jan Skoda, Madison C Pedrotty, Jennifer Vogel, Kangning Liu, Annette Vu, Erica L Carpenter, Jamie C Ye, Michelle A Chen, Peter Dunbar, Elizabeth Scadden, Taekyung D Yun, Eiko Nakamaru-Ogiso, Estela Area-Gomez, Yimei Li, Kelly C Goldsmith, C Patrick Reynolds, Gyorgy Hajnoczky, Michael D Hogarty

https://www.embopress.org/doi/full/10.15252/embj.2021108272

 

New paper in Pediatric Blood & Cancer!

Bromodomain 4 inhibition leads to MYCN downregulation in Wilms tumor. Pediatr Blood Cancer 2021, e29401.

Andrew D. Woods, Noah E. Berlow, Michael V. Ortiz, Filemon Dela Cruz, Armaan Siddiquee, Diego F. Coutinho, Reshma Purohit, Katherine E. Tranbarger Freier, Joel E. Michalek, Melvin Lathara, Kevin Matlock, Ganapati Srivivasa, Brigitte Royer-Pokora, Renata Veselska, Andrew L. Kung, Charles Keller

https://onlinelibrary.wiley.com/doi/10.1002/pbc.29401

New paper in Cancers!

Novel New Target for Precision Medicine Treatment of Giant-Cell Tumor of Bone: Sunitinib Is Effective in the Treatment of Neoplastic Stromal Cells with Activated PDGFRβ Signaling. Cancers 2021, 12:3781.

Michal Mahdal, Jakub Neradil, Peter Mudry, Silvia Paukovcekova, Iva Staniczkova Zambo, Jiri Urban, Peter Macsek, Lukas Pazourek, Tomas Tomas and Renata Veselska

https://www.mdpi.com/2072-6694/13/14/3543/htm

New paper in Cell Reports (IF 9.423)!

A selective p53 activator and anticancer agent to improve colorectal cancer therapy. Cell Rep 2021, 35(2):1089.

Helena Ramos, Maria I L Soares, Joana Silva, Liliana Raimundo, Juliana Calheiros, Célia Gomes, Flávio Reis, Filipe A Monteiro, Cláudia Nunes, Salette Reis, Bartolomeo Bosco, Silvano Piazza, Lucília Domingues, Petr Chlapek, Petr Vlcek, Pavel Fabian, Ana Teresa Rajado, A T P Carvalho, Renata Veselska, Alberto Inga, Teresa M V D Pinho E Melo, Lucília Saraiva

https://doi.org/10.1016/j.celrep.2021.108982