Novel New Target for Precision Medicine Treatment of Giant-Cell Tumor of Bone: Sunitinib Is Effective in the Treatment of Neoplastic Stromal Cells with Activated PDGFRβ Signaling. Cancers 2021, 12:3781.
Michal Mahdal, Jakub Neradil, Peter Mudry, Silvia Paukovcekova, Iva Staniczkova Zambo, Jiri Urban, Peter Macsek, Lukas Pazourek, Tomas Tomas and Renata Veselska
Our diploma student Bc. Aneta Vaskova ranked among the 31 master’s students who were awarded grant funding for her diploma project Analysis of NTRK signaling in neuroblastoma cell lines, which she conducts under the supervision by Assoc. prof. Jakub Neradil.
Congratulations and we wish you success in your research!
Our doctoral student Mgr. Lucie Curylova was awarded the prestigious three-year scholarship Brno Ph.D. talent 2020. In the competition of 130 Ph.D. students, she succeeded with her project „The p53 family proteins in the regulation of stemness in pediatric sarcomas“, whose goal is to verify the strategy of stemness factors inhibition through p53 reactivation, which might prove a promising treatment of aggressive pediatric sarcomas.
Another of our doctoral student, Mgr. Karolina Borankova, was awarded the Brno Ph.D. Talent Finalist, ranking among the best 35 attendees of the competition. Both Lucie and Karolina conduct their dissertation thesis under the supervision by Dr. Jan Skoda in our laboratory.
Congratulations on your fantastic achievement!
Paukovcekova et al.: Novel Thiosemicarbazones Sensitize Pediatric Solid Tumor Cell-Types to Conventional Chemotherapeutics through Multiple Molecular Mechanisms. Cancers 2020, 12:3781.
You can read about our research activities and this year’s results published in high-quality scientific journals on the FNUSA-ICRC website.
Paukovcekova et al.: Enhanced Antiproliferative Effect of Combined Treatment with Calcitriol and All-Trans Retinoic Acid in Relation to Vitamin D Receptor and Retinoic Acid Receptor α Expression in Osteosarcoma Cell Lines. Int. J. Mol. Sci. Art. No. 6591, 2020.
Our graduate students, Lucie Curylova and Karolina Borankova splendidly defended their Master’s theses and concluded their graduate studies with honor. Both of them will pursue their doctoral studies in our laboratory, under the supervision of dr. Skoda.
Congratulations and we are thrilled for the great results to come!
Our student Karolina Borankova has been awarded for her excellent research results obtained during her diploma thesis and she has received the Dean’s Award for the best students in the Bachelor’s or Master’s programme. In her research, Karolina focused on investigating the role of mitochondria in cancer stem cells in pediatric tumors.
Krchniakova et al.: Repurposing Tyrosine Kinase Inhibitors to Overcome Multidrug Resistance in Cancer: A Focus on Transporters and Lysosomal Sequestration. Int. J. Mol. Sci. Art. No. 3157, 2020.