Mgr. Hana Polášek-Sedláčková, Ph.D.

2025

• RECQ4-MUS81 interaction contributes to telomere maintenance with implications to Rothmund-Thomson syndrome

  ASHRAF Raghib POLÁŠEK-SEDLÁČKOVÁ Hana MARINI María Victoria PROCHÁZKOVÁ Jana HAŠANOVÁ Zdenka ZACPALOVÁ Magdaléna BOUDOVÁ Michala KREJČÍ Lumír

  Article in Periodical

  Nature Communications, year: 2025, volume: 16, edition: 1, DOI

2021

• Homologous Recombination as a Fundamental Genome Surveillance Mechanism during DNA Replication

  SPIES Julian POLÁŠEK-SEDLÁČKOVÁ Hana LUKAS Jiri SOMYAJIT Kumar

  Article in Periodical

  Genes, year: 2021, edition: 12, DOI

2020

• Equilibrium between nascent and parental MCM proteins protects replicating genomes

  SEDLÁČKOVÁ Hana RASK Maj-Britt GUPTA Rajat CHOUDHARY Chunaram SOMYAJIT Kumar LUKAS Jiri

  Article in Periodical

  Nature, year: 2020, edition: 587, DOI

2019

• Stabilization of chromatin topology safeguards genome integrity

  OCHS Fena KAREMORE Gopal MIRON Ezequiel BROWN Jill SEDLÁČKOVÁ Hana RASK Maj-Britt LAMPE Marko BUCKLE Veronica SCHERMELLEH Lothar LUKAS Jiri LUKAS Claudia

  Article in Periodical

  Nature, year: 2019, edition: 574, DOI

2017

• Redox-sensitive alteration of replisome architecture safeguards genome integrity.

  SOMYAJIT Kumar GUPTA Rajat SEDLÁČKOVÁ Hana NEELSEN Kai John OCHS Fena RASK Maj-Britt CHOUDHARY Chunaram LUKAS Jiri

  Article in Periodical

  Science, year: 2017, edition: 358, DOI

2015

• Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells

  KLISZCZAK Maciej SEDLÁČKOVÁ Hana PITCHAI Ganesha P. STREICHER Werner W. KREJČÍ Lumír HICKSON Ian D.

  Article in Periodical

  Oncotarget, year: 2015, volume: 6, edition: 38, DOI

• RECQ4 selectively recognizes Holliday junctions

  SEDLÁČKOVÁ Hana CECHOVA Barbora MLČOUŠKOVÁ Jarmila KREJČÍ Lumír

  Article in Periodical

  DNA Repair, year: 2015, volume: 30, edition: "neuvedeno", DOI

• Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates

  CHAVDAROVA Melita MARINI PALOMEQUE María Victoria SISÁKOVÁ Alexandra SEDLÁČKOVÁ Hana VIGAŠOVÁ Dana BRILL Steven J. LISBY Michael KREJČÍ Lumír

  Article in Periodical

  Nucleic Acids Research, year: 2015, volume: 43, edition: 7, DOI

2013

• Charakterizace role proteinu RecQ4 v homologní rekombinaci

  SEDLÁČKOVÁ Hana BARTOŠOVÁ Zdenka KREJČÍ Lumír

  Conference abstract

  Year: 2013, type: Conference abstract