RNDr. Miroslav Machala, CSc.

2023

• Effects of benzo[k]fluoranthene, a potent AhR ligand, on proteosynthesis and glucose metabolic regulators/effectors in liver cell models

  PETRÁŠ Jiří KARASOVÁ Martina LNĚNIČKOVÁ Anna MACHALA Miroslav ŠIMEČKOVÁ Pavlína VONDRÁČEK Jan

  Appeared in Conference without Proceedings

  Year: 2023, type: Appeared in Conference without Proceedings

2021

• A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype

  HYZDALOVA Martina PROCHÁZKOVÁ Jiřina STRAPACOVA Simona SVRZKOVA Lucie VACEK Ondřej FEDR Radek ANDRYSÍK Zdeněk HRUBA Eva LIBALOVA Helena KLEMA Jiri TOPINKA Jan MASEK Josef SOUČEK Karel VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Chemosphere, year: 2021, volume: 263, edition: January 2021, DOI

• Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes

  MACHALA Miroslav SLAVIK Josef KOVAC Ondrej PROCHÁZKOVÁ Jiřina PENCIKOVA Katerina PARENICOVA Martina STRAKOVA Nicol KOTOUCEK Jan KULICH Pavel MOLLERUP Steen VONDRÁČEK Jan HYZDALOVA Martina

  Article in Periodical

  International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 17, DOI

• Polychlorinated environmental toxicants affect sphingolipid metabolism during neurogenesis <i>in vitro</i>

  SLOVACKOVA Jana SLAVIK Josef KULICH Pavel VECERA Josef KOVAC Ondrej PACULOVA Hana STRAKOVA Nicol FEDR Radek SILVA Joao Pedro CARVALHO Felix MACHALA Miroslav PROCHÁZKOVÁ Jiřina

  Article in Periodical

  Toxicology, year: 2021, volume: 463, DOI

2020

• Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells

  VONDRÁČEK Jan PĚNČÍKOVÁ Kateřina CIGANEK Miroslav PIVNIČKA Jakub KARASOVÁ Martina HÝŽĎALOVÁ Martina STRAPÁČOVÁ Simona PÁLKOVÁ Lenka NEČA Jiří MATTHEWS Jason VOJTÍŠEK LOM Michal TOPINKA Jan MILCOVÁ Alena MACHALA Miroslav

  Article in Periodical

  Environmental Pollution, year: 2020, volume: 266, edition: November 2020, DOI

• Specific alterations of sphingolipid metabolism identified in EpCAM-positive cells isolated from human colon tumors

  PROCHÁZKOVÁ Jiřina SLAVIK Josef BOUCHAL Jan LEVKOVA Monika HUSKOVA Zlata EHRMANN Jiri OVESNÁ Petra KOLAR Zdenek SKALICKY Pavel STRAKOVA Nicol ZAPLETAL Ondrej KOZUBÍK Alois HOFMANOVÁ Jiřina VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, year: 2020, volume: 1865, edition: 9, DOI

2019

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Disrupts Control of Cell Proliferation and Apoptosis in a Human Model of Adult Liver Progenitors.

  SVOBODOVÁ Jana PROCHÁZKOVÁ Jiřina KABÁTKOVÁ Markéta KRKOŠKA Martin ŠMERDOVÁ Lenka LÍBALOVÁ Helena TOPINKA Jan KLÉMA Jiří KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  TOXICOLOGICAL SCIENCES, year: 2019, volume: 172, edition: 2, DOI

• Inhalation of ZnO Nanoparticles: Splice Junction Expression and Alternative Splicing in Mice

  RÖSSNER Pavel VRBOVÁ Kristýna STRAPÁČOVÁ Simona ROSSNEROVÁ Andrea AMBROZ Antonin BRZICOVA Tana LIBALOVÁ Helena JAVORKOVÁ Eliška KULICH Pavel VEČEŘA Zbyněk MIKUŠKA Pavel COUFALÍK Pavel KRUMAL Kamil ČAPKA Lukáš DOČEKAL Bohumil MORAVEC Pavel ŠERÝ Omar MÍŠEK Ivan FICTUM Petr FIŠER Karel MACHALA Miroslav TOPINKA Jan

  Article in Periodical

  Toxicological sciences, year: 2019, volume: 168, edition: 1, DOI

• n-3 Polyunsaturated fatty acids alter benzo[a]pyrene metabolism and genotoxicity in human colon epithelial cell models

  TYLICHOVÁ Zuzana NECA Jiri TOPINKA Jan MILCOVA Alena HOFMANOVÁ Jiřina KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  Food and Chemical Toxicology, year: 2019, volume: 124, edition: FEB 2019, DOI

2018

• Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands

  PROCHÁZKOVÁ Jiřina STRAPÁČOVÁ Simona SVRŽKOVÁ Lucie ANDRYSÍK Zdeněk HYZDALOVA Martina HRUBÁ Eva PĚNČÍKOVÁ Kateřina LIBALOVA H TOPINKA J KLÉMA Jiří ESPINOSA JM VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Toxicology Letters, year: 2018, volume: 292, DOI