2018

• Presence of growth/differentiation factor-15 cytokine in human follicular fluid, granulosa cells, and oocytes

  SOUČEK Karel MALENOVSKÁ Alice KAHOUNOVÁ Zuzana REMŠÍK Ján HOLUBCOVÁ Zuzana SOUKUP Tomáš KURFÜRSTOVÁ Daniela BOUCHAL Jan SUCHANKOVÁ Tereza SLABÁKOVÁ Eva HAMPL Aleš

  Article in Periodical

  Journal of Assisted Reproduction and Genetics, year: 2018, volume: 35, edition: 8, DOI

• Selective CHK1 inhibitor MU380 exhibits single-agent activity against chronic lymphocytic leukemia cells with TP53 mutations

  BOUDNÝ Miroslav ZEMANOVÁ Jana KHIRSARIYA PrashantKumar BORSKÝ Marek VERNER Jan ČERNÁ Jana MRÁZ Marek OLTOVÁ Alexandra JAŠKOVÁ Zuzana ŠPUNAROVÁ Michaela ŠEDA Václav BRYCHTOVÁ Yvona MAYER Jiří PARUCH Kamil TRBUŠEK Martin

  Conference abstract

  Year: 2018, type: Conference abstract

• The fibroblast surface markers FAP, anti-fibroblast, and FSP are expressed by cells of epithelial origin and may be altered during epithelial-to-mesenchymal transition

  KAHOUNOVA Zuzana KURFURSTOVA Daniela BOUCHAL Jan KHARAISHVILI Gvantsa NAVRATIL Jiri REMŠÍK Ján ŠIMEČKOVÁ Šárka ŠTUDENT Vladimír KOZUBÍK Alois SOUČEK Karel

  Article in Periodical

  Cytometry Part A, year: 2018, volume: 93A, edition: 9, DOI

2017

• Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells

  BOSTROM Johan ŠRÁMKOVÁ Zuzana SALAŠOVÁ Alena JOHARD Helena Anna Dagmar MAHDESSIAN Diana FEDR Radek MARKS Carolyn MEDALOVÁ Jiřina SOUČEK Karel LUNDBERG Emma LINNARSON Sten BRYJA Vítězslav SEKYROVÁ Petra ALTUN Mikael ANDÄNG Michael

  Article in Periodical

  PLOS ONE, year: 2017, volume: 12, edition: 12, DOI

• Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

  SAMADDER Pounami SUCHÁNKOVÁ Tereza HYLSE Ondřej KHIRSARIYA PrashantKumar NIKULENKOV Fedor DRÁPELA Stanislav STRAKOVÁ Nicol VAŇHARA Petr VAŠÍČKOVÁ Kateřina KOLÁŘOVÁ Hana BINÓ Lucia BITTOVÁ Miroslava OVESNÁ Petra KOLLÁR Peter FEDR Radek EŠNER Milan JAROŠ Josef HAMPL Aleš KREJČÍ Lumír PARUCH Kamil SOUČEK Karel

  Article in Periodical

  Molecular Cancer Therapeutics, year: 2017, volume: 16, edition: 9, DOI

2016

• Cancer TARGETases: DSB Repair as a Pharmacological Target

  SAMADDER Pounami AITHAL Rakesh BELÁŇ Ondrej KREJČÍ Lumír

  Article in Periodical

  Pharmacology & Therapeutics, year: 2016, volume: 161, edition: "May", DOI

• Checkpoint kinase 1 inhibition potentiates apoptosis and inflicts mitotic failure in CLL-derived MEC-1 cell line.

  ZEMANOVÁ Jana HYLSE Ondřej ČOLLÁKOVÁ Jana VESELÝ Petr OLTOVÁ Alexandra PARUCH Kamil TRBUŠEK Martin

  Conference abstract

  Year: 2016, type: Conference abstract

• Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells

  ZEMANOVÁ Jana HYLSE Ondřej COLLAKOVA Jana VESELY Pavel OLTOVÁ Alexandra BORSKÝ Marek ZÁPRAŽNÁ Kristína KAŠPÁRKOVÁ Marie JANOVSKÁ Pavlína VERNER Jan KOHOUTEK Jiri DZIMKOVA Marta BRYJA Vítězslav JAŠKOVÁ Zuzana BRYCHTOVÁ Yvona PARUCH Kamil TRBUŠEK Martin

  Article in Periodical

  Oncotarget, year: 2016, volume: 7, edition: 38, DOI