Project information
Biologická úloha lektinů v symbióze a patogenezi

Project Identification

GA21-29622S

Project Period

1/2021 - 12/2023

Investor / Pogramme / Project type

Czech Science Foundation

Standard Projects

MU Faculty or unit

Faculty of Science

Navrhovaný projekt je zaměřen na studium úlohy lektinů v symbióze a patogenezi v tripartitních systémech, ve kterých se neuplatňuje pouze jednoduchý bivalentní vztah hostitel-patogen. Budeme primárně studovat význam lektinů z klíštěte obecného a lektinů
z bakterií Photorhabdus spp., jež patří mezi lidské i hmyzí patogeny žijící symbióze s hlísticemi Heterorhabditis spp., se snahou pochopit jejich zapojení komplexních patogenních systémech
bakterie-přenašeč-hostitel.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Publications

Total number of publications: 11

2025

Bispecific Thio-linked Disaccharides as Inhibitors of Pseudomonas aeruginosa Lectins LecA (PA-IL) and LecB (PA-IIL): Dual-Targeting Strategy

FALTINEK Lukáš MELICHER Filip KELEMEN Viktor MEZŐ Erika BORBÁS Anikó WIMMEROVÁ Michaela

Article in Periodical

Chemistry – A European Journal, year: 2025, volume: 31, edition: 5, DOI

2023

Dual specificity of PLL2 lectin

PAULENOVÁ Eva HOUSER Josef MELICHER Filip WIMMEROVÁ Michaela

Conference abstract

Year: 2023, type: Conference abstract
Production of recombinant lectin PluLec from Photorhabdus luminescens for neutron crystallography and its structure-functional characterization.

KORSÁK Marek HOUSER Josef DEVOS Juliette GAJDOŠ Lukáš DOBEŠ Pavel WIMMEROVÁ Michaela

Appeared in Conference without Proceedings

Year: 2023, type: Appeared in Conference without Proceedings

2022

Detailed analysis of binding sites in the PLL family

FUJDIAROVÁ Eva HOUSER Josef MELICHER Filip FALTINEK Lukáš WIMMEROVÁ Michaela

Conference abstract

Year: 2022, type: Conference abstract
Development of lectin arrays for mapping the glycosylation changes in proteins and cells

KOMÁREK Jan KORSÁK Marek FALTINEK Lukáš WIMMEROVÁ Michaela

Conference abstract

Year: 2022, type: Conference abstract
Searching for New Lectins in Mushrooms

MALINOVSKÁ Lenka ZIMOVÁ Kamila PONČÁKOVÁ Dominika JUZA Vojtěch WIMMEROVÁ Michaela

Conference abstract

Year: 2022, type: Conference abstract
Seven-bladed beta-propeller lectins from entomopathogenic bacterium Photorhabdus laumondii

PAULENOVÁ Eva DOBEŠ Pavel HOUSER Josef MELICHER Filip FALTINEK Lukáš HYRŠL Pavel WIMMEROVÁ Michaela

Appeared in Conference without Proceedings

Year: 2022, type: Appeared in Conference without Proceedings
Studying the role of PLLs, the family of lectins produced by Photorhabdus sp., the bacterial symbiont of entomopathogenic nematodes

DOBEŠ Pavel FUJDIAROVÁ Eva HOUSER Josef HYRŠL Pavel WIMMEROVÁ Michaela

Conference abstract

Year: 2022, type: Conference abstract

2021

New "Blood" in Lectin Research

MALINOVSKÁ Lenka WIMMEROVÁ Michaela

Conference abstract

Year: 2021, type: Conference abstract
PLL-like lectin family from entomopathogenic bacterium Photorhabdus laumondii

FUJDIAROVÁ Eva DOBEŠ Pavel HOUSER Josef MELICHER Filip FALTINEK Lukáš HYRŠL Pavel WIMMEROVÁ Michaela

Appeared in Conference without Proceedings

Year: 2021, type: Appeared in Conference without Proceedings