Project information
Exploring the mechanism of polyhydroxybutyrate regulation in Paracoccus denitrificans (PdenPHB)

Project Identification
MUNI/IGA/1166/2020
Project Period
1/2021 - 12/2021
Investor / Pogramme / Project type
Masaryk University
MU Faculty or unit
Faculty of Science

Paracoccus denitrificans is N2-evolving bacterium producing polyhydroxybutyrate (PHB). Preliminary data indicate more complex regulatory connections between metabolic pathways of inorganic nitrogen and PHB than we previously thought. Studies require bioreactors, qRT-PCR, GC and chemical derivatization, possibly gene knock-outs. PHB analysis could be utilized for educational purposes. Internship in 2021 at Stockholm University, Sweden at prof. Pia Ädelroth’s research group is arranged.

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