Successor Sequence Prediction: A Novel Strategy to Foresee Proteins’ Evolutionary Trajectories (FORESIGHT (FORESee Evolutionary Trajectories))

Project Identification
MUNI/IGA/1327/2021
Project Period
1/2022 - 12/2022
Investor / Pogramme / Project type
Masaryk University
MU Faculty or unit
Faculty of Science

Ancestral Sequence Reconstruction (ASR) is a powerful technique that allows researchers to build the evolutionary history of modern proteins. However there are no known techniques that allow predicting what will come after the modern proteins, i.e., what will be the protein sequence of a ‘Successor’, in the future. Using datasets for amino acids, such as the AAIndex, a Successor sequence may be calculated.

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