Another paper out and another step closer to a better understanding of #RNF43 tumor #suppressor action thanks to Tomek Radaszkiewicz from Bryjalab! Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells … Read More
Stem Cell Res. 2020 May;45:101770 ABSTRACT: Embryonic neural stem cells (NSCs), comprising neuroepithelial and radial glial cells, are indispensable precursors of neurons and glia in the mammalian developing brain. Since the process of neurogenesis occurs in a hypoxic environment, the … Read More
Insects 2020, 11(6), 353; https://doi.org/10.3390/insects11060353 ABSTRACT: Entomopathogenic nematodes (EPNs) are efficient insect parasites, that are known for their mutualistic relationship with entomopathogenic bacteria and their use in biocontrol. EPNs produce bioactive molecules referred to as excreted/secreted products (ESPs), which have … Read More
Elsevier Collection of Neuroscience and Biobehavioral Psychology, https://doi.org/10.1016/B978-0-12-809324-5.24159-X ABSTRACT: The discovery of magnetic sensitivity in invertebrates such as Drosophila, the cockroach Periplaneta americana, or the nematode Caenorhabditis elegans make us reconsider our intuitive and possibly too anthropocentric views about the … Read More
Development 2020 147: dev186338 ABSTRACT: Directional migration during embryogenesis and tumor progression faces the challenge that numerous external signals need to converge to precisely control cell movement. The Rho guanine exchange factor (GEF) Trio is especially well suited to relay … Read More
Helena Modra, Miroslava Palikova, Pavel Hyrsl, Jana Bartonkova, Ivana Papezikova, Zdenka Svobodova, Jana Blahova, Jan Mares The aim of this study was to assess the effects of T-2 toxin–contaminated feed (at concentrations of 1.0 and 1.8 mg/kg) on the rainbow … Read More
ABSTRACT: Bumble bees are important pollinators broadly used by farmers in greenhouses and under conditions in which honeybee pollination is limited. As such, bumble bees are increasingly being reared for commercial purposes, which brings into question whether individuals reared under … Read More
Cells 2020, 9(5), 1147. ABSTRACT Wnt and BMP signaling pathways are two key molecular machineries regulating development and homeostasis. The efficient coordination of Wnt and BMP is essential in many developmental processes such as establishment of antero-posterior and dorso-ventral body … Read More
PLoS One. 2020 Mar 25;15(3):e0229170. doi: 10.1371/journal.pone.0229170. ABSTRACT: Surface protein CD20 serves as the critical target of immunotherapy in various B-cell malignancies for decades, however its biological function and regulation remain largely elusive. Better understanding of CD20 function may help … Read More
Lead oxide nanoparticles (PbONPs), upon their entry into the lungs via inhalation, induce structural changes in primary and secondary target organs. The fate and ultrastructural localization of PbONPs in organs is known to be dependent on the specific organ. Here, … Read More