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Latest Publications from Our Section

Polarized Sonic Hedgehog Protein Localization and a Shift in the Expression of Region-Specific Molecules Is Associated With the Secondary Palate Development in the Veiled Chameleon
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Secondary palate development is characterized by the formation of two palatal shelves on the maxillary prominences, which fuse in the midline in mammalian embryos. However, in reptilian species, such as turtles, crocodilians, and lizards, the palatal shelves of the secondary … Read More

Choroid Plexus: The Orchestrator of Long-Range Signalling Within the CNS
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A comprehensive review on choroid plexus and its regulatory role in CNS by Karol Kaiser, Ph.D. just published in International Journal of Molecular Sciences! Follow us on Twitter. 😉

Heptabladed β‐propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O‐methylated sugars and influence the host immune system
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O‐methylation is an unusual sugar modification with a function that is not fully understood. Given its occurrence and recognition by lectins involved in the immune response, methylated sugars were proposed to represent a conserved pathogen‐associated molecular pattern. We describe the … Read More

Seroprevalence of Antibodies against Borrelia burgdorferi s. l. and Leptospira interrogans s. l. in Cats in district of Brno and its environs, the Czech Republic
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Objectives:The aim of this study is to evaluate the seroprevalence of antibodies of Borrelia burgdorferi sensu lato (Bbsl) and Leptospira interrogans sensu lato (Lisl) and their possible concurrence in domestic cats living in variable conditions in South Moravia in the … Read More

Protease Associated Domain of RNF43 Is Not Necessary for the Suppression of Wnt/β-catenin Signaling in Human Cells
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Another paper out and another step closer to a better understanding of #RNF43 tumor #suppressor action thanks to Tomek Radaszkiewicz from Bryjalab!   Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells … Read More

Hypoxia/Hif1α Prevents Premature Neuronal Differentiation of Neural Stem Cells Through the Activation of Hes1
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Stem Cell Res. 2020 May;45:101770 ABSTRACT: Embryonic neural stem cells (NSCs), comprising neuroepithelial and radial glial cells, are indispensable precursors of neurons and glia in the mammalian developing brain. Since the process of neurogenesis occurs in a hypoxic environment, the … Read More