Brief description

The institution caters for research topics ranging from veterinary to biomedical applications and further to general issues of basic research. The problems represented include especially those of cell signalling, which are crucial for the understanding of the processes that control the embryonic development, differentiation of tissues and their regeneration, as well as processes of carcinogenesis or immunity regulations.

The PhD program Animal Physiology, Immunology and Developmental Biology is focused on the study of current problems of modern biology. The research is conducted both on models of whole animal organisms and on the cellular level where techniques of molecular biology are employed.

The spectrum of immunity issues is resolved on a wide range of organisms, from invertebrates across fishes and farm animals to man. The department has been also specialized in the model group of insects, where neuro-ethological and immunological problems have been investigated. Thus, the field integrates methodical approaches of molecular biology, genetics and cellular biology with morphological and behavioural aspects.

Our graduates are prepared for a career in both research- and application-oriented institutions. The wide spectrum of themes resolved in co-operation with a number of training institutions outside the Faculty provides the graduates with the possibility of
finding vacancies both in the top-ranking biomedical research and at the
associated clinical institutions of human medicine.

The aim of the Animal Physiology, Immunology and Developmental Biology PhD program is to prepare the PhD students for independent scientific career and to equip them with the knowledge and skills required for work in a wide spectrum of institutions on the international level.

Supervisors – Research groups that you can join

Prof. Vitezslav Bryja – Cellular Communication

Mechanisms and components of Wnt signalling pathway, Wnt signalling in the pathogenesis of chronic lymphocytic leukaemia and ovarian cancer, extracellular vesicles, proteomics in cell biology; more info

Assoc. prof. Marcela Buchtova – Molecular and Comparative Morphogenesis

Molecular and cellular processes during embryonal and postnatal development, intercellular interactions involved in changes in cell proliferation and their differentiation in tissues during development, mechanisms involved in lip cleft formation, palate and other defects in the craniofacial region, mechanisms of limb development, including related disorders; more info

Assoc. prof. Pavel Hyrsl – Comparative Immunology, Pathogen-Host Interaction

Innate immunity of insects and its molecular nature, the role of eicosanoids in insect immune reactions, entomopathogenic nematodes and their effect on host immune responses, bacteria of the genus Photorhabdus and the effect of their products on the immune system, immunology of fish and birds; more info

Dr. Jiri Pachernik & Dr. Jirina Medalova – Stem Cells and Cell Biotechnology

Myocardial stem cell biology and neural stem cells, pluripotent stem cells and cardiomyogenesis, regulation of cardiomyocyte phenotype, 3D myocardial bioprint, neural stem cells and neurogenesis, analysis of biocompatibility of artificial materials for biomedicine; more info


Profiles of our graduates