Project information
Lectins from Burkholderia venocepacia: structure-function studies

Project Identification
MEB020710
Project Period
1/2008 - 12/2008
Investor / Pogramme / Project type
Ministry of Education, Youth and Sports of the CR
MU Faculty or unit
Faculty of Science
Keywords
Burkholderia cenocepacia, cystic fibrosis, lectins, pathogens

Biomolecular interactions play a crucial role in living systems where they are used not only for recognition but they are involved in information transfer and communication in living system in general. Carbohydrate-mediated recognition is important in many physiological processes including fertilization, pathogen-cell adhesion and recognition, signaling, inflammatory response and others. The main goal of the sugested co-operation is an identification and characterisation of B. cepacia lectins and structure-function analysis of their interactions with biologically active oligosaccharides.

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