Project information
CZ-OPENSCREEN: National Infrastructure for Chemical Biology
(CZ-OPENSCREEN)
- Project Identification
- LM2018130
- Project Period
- 1/2020 - 12/2022
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Faculty of Science
- Cooperating Organization
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Institute of Molecular Genetics of the ASCR, v. v. i.
- Responsible person RNDr. Petr Bartůněk, CSc.
Prague Institute of Chemical Technology
The aim of the project „CZ-‐OPENSCREEN: National infrastructure for chemical biology” is to operate the state-‐of-‐the-‐art infrastructure for basic and applied research in the fields of chemical biology and genetics and provide Open Access to users. It will serve as the National node of the pan-European ESFRI infrastructure EU-‐OPENSCREEN, providing trans-‐national access to the Screening platform and to the European Chemical Biology Library. The mission of CZ-‐OPENSREEN is to identify new molecular probes/tools for research and new potential therapeutics.
Publications
Total number of publications: 21
2023
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4-(1H-IMIDAZOL-5-YL)-1H-PYRROLO [2,3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS
Publisher: China National Intellectual Property Administration, state: China, patent's number: CN111936496, year: 2023
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Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity
Angewandte Chemie International Edition, year: 2023, volume: 62, edition: 11, DOI
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Substituted aminothiazoles as inhibitors of nucleases
Publisher: United States Patent and Trademark Office, state: United States of America, patent's number: US11584742, year: 2023
2022
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4-(1h- imidazol- 5- yl) -1h-pyrrolo [2, 3-b] pyridines for use in the treatment of leukaemias, lymphomas and solid tumors
Publisher: Canadian Intellectual Property Office, state: Canada, patent's number: CA3085967, year: 2022
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4-(1h- imidazol- 5- yl) -1h-pyrrolo [2, 3-b] pyridines for use in the treatment of leukaemias, lymphomas and solid tumors
Publisher: European Patent Office, state: Germany, patent's number: EP3774795, year: 2022
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4-(1H-imidazol-5-yl)-1H-pyrrolo[2, 3-b] pyridines for use in the treatment of leukaemias, lymphomas and solid tumors
Publisher: United States Patent and Trademark Office, state: United States of America, patent's number: US11498920, year: 2022
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CDK11 regulates pre-mRNA splicing by phosphorylation ofSF3B1
NATURE, year: 2022, volume: 609, edition: 7928, DOI
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Comparing the efficiency of six clearing methods in developing seeds of Arabidopsis thaliana
Plant Reproduction, year: 2022, volume: 35, edition: 4, DOI
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Geometric Control of Cell Behavior by Biomolecule Nanodistribution
ACS BIOMATERIALS SCIENCE & ENGINEERING, year: 2022, volume: 8, edition: 11, DOI
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Substituted aminothiazoles as inhibitors of nucleases
Publisher: IP Australia, state: Australia, patent's number: AU2019256670, year: 2022