Project information
Characterization of intrinsically disordered proteins

Information

This project doesn't include Faculty of Science. It includes Central European Institute of Technology. Official project website can be found on muni.cz.

Project Identification

GF20-05789L

Project Period

1/2020 - 12/2022

Investor / Pogramme / Project type

Czech Science Foundation

LA Grants

MU Faculty or unit

Central European Institute of Technology

doc. RNDr. Mgr. Jozef Hritz, Ph.D.

Cooperating Organization

Universität für Bodenkultur Wien

Responsible person Chris Oostenbrink

We will characterize the conformational ensembles of RD-TyrH, Map2c and tau. We hypothesize that shifts in the conformational ensembles of these IDPs/IDRs are crucial to understand their function and will further develop integrative experimental and computational approaches to characterize these shifts.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Publications

Total number of publications: 18

2023

14-3-3 dimer vs monomer – (dis)similarities in Tau protein binding

KOZELEKOVÁ Aneta IĽKOVIČOVÁ Lucia CRHA Radek HOFROVÁ Alena HRITZ Jozef

Conference abstract

Year: 2023, type: Conference abstract
Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region

LASORSA Alessia BERA Krishnendu MALKI Idir DUPRE Elian CANTRELLE Francois-Xavier MERZOUGUI Hamida SINNAEVE Davy HANOULLE Xavier HRITZ Jozef LANDRIEU Isabelle

Article in Periodical

Biochemistry, year: 2023, volume: 62, edition: 11, DOI
Conformational changes upon phosphorylation of proline rich region of tau(210-240) peptide using molecular dynamic simulation

BERA Krishnendu LANDRIEU Isabelle HRITZ Jozef

Conference abstract

Year: 2023, type: Conference abstract
Designing of Insecticides Against Bemisia tabaci targeting ecdysone receptor

BERA Krishnendu HRITZ Jozef BRÁZDA Václav KUMAR Rajesh BERA Krishnendu

Conference abstract

Year: 2023, type: Conference abstract
Interaction of selected drugs at dimer interface of human 14-3-3ζ protein

BERA Krishnendu HRITZ Jozef

Conference abstract

Year: 2023, type: Conference abstract
Molecular dynamic simulation study of multiple phosphorylations at the proline rich region of tau(210-240) peptide

BERA Krishnendu ALESSIA Lasorsa LANDRIEU Isabelle HRITZ Jozef ALESSIA Lasorsa HRITZ Jozef

Conference abstract

Year: 2023, type: Conference abstract

2022

14-3-3 protein isoforms: mutual dimerization propensities screening kit

ŠIMEK Jan KRÁLOVÁ Kateřina HRITZ Jozef

Conference abstract

Year: 2022, type: Conference abstract
A new fibrillization mechanism of β-lactoglobulin in glycine solutions

JAKLIN M. HRITZ Jozef HRIBAR-LEE B.

Article in Periodical

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, year: 2022, volume: 216, edition: SEP, DOI
Biomolecular Complexation on the "Wrong Side": A Case Study of the Influence of Salts and Sugars on the Interactions between Bovine Serum Albumin and Sodium Polystyrene Sulfonate

SIMONČIČ Matjaž HRITZ Jozef LUKŠIČ Miha

Article in Periodical

Biomacromolecules, year: 2022, volume: 23, edition: 10, DOI
Impact of Chromate and Dichromate on Lysozyme Stability: A Spectroscopic and Molecular Docking Investigation

SUBADINI Suchismita PANIGRAHY Ram Sankar GUPTA Nishesh Kumar BERA Krishnendu SAHOO Harekrushna

Article in Periodical

Luminescence, year: 2022, volume: 37, edition: 6, DOI