CIISB - Czech Infrastructure for Integrative Structural Biology (CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 20
2023
-
Advanced Microscopic and Biosensing Approaches for Monitoring Bacteriophage-Mediated Lysis of Bacteria
Year: 2023, type: Conference abstract
-
Autophagy modulators influence the content of important signalling molecules in PS-positive extracellular vesicles
Cell Communication and Signaling, year: 2023, volume: 21, edition: 1, DOI
-
Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide
Cellular & Molecular Biology Letters, year: 2023, volume: 28, edition: 1, DOI
-
Development of lectin arrays for mapping the glycosylations of proteins and cells
Year: 2023, type: Conference abstract
-
DiaPASEF proteotype analysis indicates changes in cell growth and metabolic switch induced by caspase-9 inhibition in chondrogenic cells
Proteomics, year: 2023, volume: 23, edition: 11, DOI
-
Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate
Molecular Neurodegeneration, year: 2023, volume: 18, edition: 1, DOI
-
Dual specificity of PLL2 lectin
Year: 2023, type: Conference abstract
-
Effect of titanium nanostructured surface on fibroblast behavior
Journal of Biomedical Materials Research Part A, year: 2023, DOI
-
Enantioselective trihalohydroxyalkylation of activated phenols
Year: 2023, type: Appeared in Conference without Proceedings
-
Extraction Protocol for Parallel Analysis of Proteins and DNA from Ancient Teeth and Dental Calculus
Journal of Proteome Research, year: 2023, volume: 22, edition: 10, DOI