Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 94
2024
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37th Central European NMR Meeting, NMR Valtice 2024
Year: 2024, type: Conference
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A hybrid DDA/DIA-PASEF based assay library for a deep proteotyping of triple-negative breast cancer
Scientific Data, year: 2024, volume: 11, edition: 1, DOI
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A Platform for the Synthesis of Oxidation Products of Bilirubin
Journal of the American Chemical Society, year: 2024, volume: 146, edition: 2, DOI
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A reusable QCM biosensor with stable antifouling nano-coating for on-site reagent-free rapid detection of E. coli O157:H7 in food products
Food Control, year: 2024, volume: 165, edition: November 2024, DOI
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Anticholinesterase Activity of Methanolic Extract of Amorpha fruticosa Flowers and Isolation of Rotenoids and Putrescine and Spermidine Derivatives
PLANTS-BASEL, year: 2024, volume: 13, edition: 9, DOI
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Asymmetric Organocatalyzed Transfer Hydroxymethylation of Isoindolinones Using Formaldehyde Surrogates
Organic Letters, year: 2024, volume: 12, edition: 26, DOI
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Caspase-9 Is a Positive Regulator of Osteoblastic Cell Migration Identified by diaPASEF Proteomics
Journal of Proteome Research, year: 2024, volume: 23, edition: 8, DOI
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CF Day 2023
Year: 2024, type: Popularization text
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Comparison of phosphopeptide enrichment and LC-MS/MS acquisition methods to study cancer phosphoproteome
Year: 2024, type: Conference abstract
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Correlating plasma protein profiles with symptomatology and treatment response in acute phase and early remission of major depressive disorder
Frontiers in Psychiatry, year: 2024, volume: 15, edition: September 2024, DOI