Informace o projektu
Národní centrum lékařské genomiky
(NCLG)
- Kód projektu
- LM2018132
- Období řešení
- 1/2020 - 12/2022
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
- Spolupracující organizace
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Univerzita Karlova v Praze
- Odpovědná osoba prof. Ing. Stanislav Kmoch, CSc.
National Centre of Medical Genomics (NCMG) is the only research infrastructure in the Roadmap for Large Research, Development and Innovation Infrastructures of the Czech Republic focused on medical genomics. Local (national) genomic infrastructure is the only way how we can unite genomic experts, clinicians, scientist, patients and industry to study, identify and understand causes of individual and population specific diseases. Interdisciplinary collaboration will increase competitiveness of Czech biomedical science and our recent results clearly document, that this approach leads to significant discoveries (e.g. identification of causal genes and elucidation of molecular basis of > 20 human genetic diseases, leukemia, aspergillosis, inherited neurodegenerative and neuromuscular diseases, skin diseases and metabolics diseases), may attract foreign investigators to use the expertize and may have economic impact (new diagnostic products introduced on the market thanks to collaboration of MU and company Generi BioTech). Infrastructure is also important for education and training of new generation of scientists, computing specialists, bioinformaticians, statisticians, instrument operators, clinical genomicists and clinicians. All participating groups are involved in pregraduate and postgraduate education as well as in organization of specialised training programs and courses and organisation of workshops and symposia.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 72
2022
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Transcriptomic and proteomic profiling of peptidase expression in Fasciola hepatica eggs developing at host's body temperature
SCIENTIFIC REPORTS, rok: 2022, ročník: 12, vydání: 1, DOI
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Very rare near-haploid acute lymphoblastic leukemia resistant to immunotherapy and CAR-T therapy in 19-year-old male patient
CLINICAL CASE REPORTS, rok: 2022, ročník: 10, vydání: 3, DOI
2021
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Business Research Forum
Rok: 2021, druh: Popularizační texty
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CF Day
Rok: 2021, druh: Uspořádání konference
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Complex Interplay of Genes Underlies Invasiveness in Fibrosarcoma Progression Model
Journal of Clinical Medicine, rok: 2021, ročník: 10, vydání: 11, DOI
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Distribution of SARS-CoV-2 Lineages in the Czech Republic, Analysis of Data from the First Year of the Pandemic
Microorganisms, rok: 2021, ročník: 9, vydání: 8, DOI
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Evolution of plant telomerase RNAs: farther to the past, deeper to the roots
Nucleic acids research, rok: 2021, ročník: 49, vydání: 13, DOI
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FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia
Blood, rok: 2021, ročník: 138, vydání: 9, DOI
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Functional analysis of new variant GP1BA gene in inherited macrotrombocytopenia.
Rok: 2021, druh: Konferenční abstrakty
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Histopathology of laboratory-reared Nothobranchius fishes: Mycobacterial infections versus neoplastic lesions
Journal of Fish Diseases, rok: 2021, ročník: 44, vydání: 8, DOI