CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells

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PLoS One. 2020 Mar 25;15(3):e0229170. doi: 10.1371/journal.pone.0229170.   Kozlova V, Ledererova A, Ladungova A, Peschelova H, Janovska P, Slusarczyk A, Domagala J, Kopcil P, Vakulova V, Oppelt J, Bryja V, Doubek M, Mayer J, Pospisilova S, Smida M. Surface protein … Read More

Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs.

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Cell Communication and Signaling volume 17, Article number: 170 (2019) BACKGROUND: Dishevelled (DVL) is an essential component of the Wnt signaling cascades. The function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and threonines whose … Read More

The effects of nano-sized PbO on biomarkers of membrane disruption and DNA damage in a sub-chronic inhalation study on mice

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Although the production of engineered nanoparticles increases our knowledge of toxicity and mechanisms of bioactivity during relevant exposures is lacking. In the present study, mice were exposed to PbO nanoparticles (PbONP; 192.5 µg/m3; 1.93 × 106 particles/cm3) for 2, 5 and 13 weeks through … Read More

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